Biomimetic double network hydrogels: Combining dynamic and static crosslinks to enable biofabrication and control cell‐matrix interactions

Unification of Static and Dynamic Analyses to Enable Vectorization

Modern compilers execute sophisticated static analyses to enable optimization across a wide spectrum of code patterns. However, there are many cases where even the most sophisticated static analysis is insufficient or where the computation complexity makes complete static analysis impractical. It is often possible in these cases to discover further opportunities for optimization from dynamic pr...

Detecting Control Flow in Smarphones: Combining Static and Dynamic Analyses

Security in embedded systems such as smartphones requires protection of confidential data and applications. Many of security mechanisms use dynamic taint analysis techniques for tracking information flow in software. But these techniques cannot detect control flows that use conditionals to implicitly transfer information from objects to other objects. In particular, malicious applications can b...

Strategies To Increase the Thermal Stability of Truly Biomimetic Hydrogels: Combining Hydrophobicity and Directed Hydrogen Bonding

Enhancing the thermal stability of proteins is an important task for protein engineering. There are several ways to increase the thermal stability of proteins in biology, such as greater hydrophobic interactions, increased helical content, decreased occurrence of thermolabile residues, or stable hydrogen bonds. Here, we describe a well-defined polymer based on β-helical polyisocyanotripeptides ...

Acrylamide Polymer Double-Network Hydrogels

Background: In focal repair of joint cartilage and meniscus, initial stiffness and strength of repairs are generally much less than surrounding tissue. This increases early failure potential. Secure primary fixation of the repair material is also a problem. Acrylamide polymer double-network (DN) hydrogels are candidate-improved repair materials. DN gels have exceptional strength and toughness c...

Fatigue of double-network hydrogels